PETA

Sustaining strong results for an 18-year control package is no easy feat, even if you’re an aggressive direct mailer such as the People for the Ethical Treatment of Animals, which dropped 7 million cold-mail acquisition pieces in its last fiscal year alone.

And while it’s no surprise that PETA’s pack has seen myriad tweaks and tests and format changes over the years, the nexus has been a simple, straightforward questionnaire, with jarring inquiries such as: “Did you realize that the vast majority of painful animal experimentation has no relation at all to human survival or the elimination of disease?”